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Spending Function

Usage

spendingFunction(alpha, t, param)

Arguments

alpha

Real value \(> 0\) and no more than 1. Defaults in calls to gsDesignCRT() are alpha=0.025 for one-sided Type I error specification and alpha=0.1 for Type II error specification. However, this could be set to 1 if, for descriptive purposes, you wish to see the proportion of spending as a function of the proportion of sample size/information.

t

A vector of points with increasing values from 0 to 1, inclusive. Values of the proportion of sample size/information for which the spending function will be computed.

param

A single real value or a vector of real values specifying the spending function parameter(s); this must be appropriately matched to the spending function specified.

Value

spendingFunction and spending functions in general produce an object of type spendfn.

name

A character string with the name of the spending function.

param

any parameters used for the spending function.

parname

a character string or strings with the name(s) of the parameter(s) in param.

sf

the spending function specified.

spend

a vector of cumulative spending values corresponding to the input values in t.

bound

this is null when returned from the spending function, but is set in gsDesignCRT() if the spending function is called from there. Contains z-values for bounds of a design.

prob

this is null when returned from the spending function, but is set in gsDesignCRT() if the spending function is called from there. Contains probabilities of boundary crossing at i-th analysis for j-th theta value input to gsDesignCRT() in prob[i,j].

Note

The gsDesign technical manual is available at https://keaven.github.io/gsd-tech-manual/.

References

Jennison C and Turnbull BW (2000), Group Sequential Methods with Applications to Clinical Trials. Boca Raton: Chapman and Hall.

See also

gsDesignCRT, sfHSD, sfPower, sfLogistic, sfExponential, sfTruncated, vignette("gsDesignCRTPackageOverview")

Author

Keaven Anderson keaven_anderson@merck.com